Medical Researches
Possibly Effective
Based on 64 Researches
DHA in cod liver oil benefits heartDocosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Cod liver oil's impact explored
We explored the effects of docosahexaenoic acid (DHA), a key component of cod liver oil, on heart health, especially after a heart attack. The study investigated whether DHA could play a role in protecting the heart from damage caused by myocardial infarction (MI).
Using both lab-based and animal models, we observed that DHA not only improved the survival of heart cells affected by low oxygen but also reduced overall heart area damage in mice after an MI. Remarkably, we found that DHA enhanced the body's natural process of autophagy, which helps clear out damaged cells and supports heart function.
With the inhibition of autophagy, we noted that the beneficial effects of DHA diminished, underscoring the importance of this process in heart protection. The study showed that DHA works through a specific signaling pathway, the AMPK/mTOR pathway, which is essential for autophagy and improved heart health.
Overall, our findings suggest that incorporating DHA, as found in cod liver oil, could be a promising strategy to support heart health after a heart attack and reduce long-term damage.
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Cod liver oil aids heart healthCod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats.
Directly addresses heart disease
We delved into how cod liver oil (CLO) influences heart health, especially in the context of diabetes. Using a study with streptozotocin (STZ)-induced diabetic rats, we treated them with CLO and monitored various cardiovascular metrics over 12 weeks. What we found was quite telling: untreated diabetic rats faced significant increases in blood sugar and harmful lipid levels, while those receiving CLO showed improved weight gain and complete prevention of lipid problems.
Moreover, the study revealed that CLO-treated rats exhibited healthier blood vessel responses and heart function. For instance, we observed that CLO effectively corrected some vasoconstriction issues and improved heart rhythm responses that were otherwise diminished in diabetic rats. The treatment also helped preserve the structural integrity of heart tissue, which often suffers in diabetes.
Overall, this research strongly suggests that cod liver oil can be a valuable supplement for mitigating heart disease risks associated with diabetes. With its rich omega-3 fatty acids and antioxidants, CLO appears to play a protective role in maintaining cardiovascular health in diabetic settings.
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Cod liver oil aids heart recovery[Correction of disorders of cardiac electric stability in post-infarction cardiosclerosis using a diet enriched with polyunsaturated fatty acids].
Direct impact on heart disease
We conducted a study to investigate how cod liver oil, rich in beneficial fatty acids, affects heart health, especially after a heart attack. We fed rats a substance called "eikonole," derived from cod liver oil and enriched with eicosapentaenoic (EPA) and docosahexaenoic (DHA) fatty acids. Following this feeding period, we induced a myocardial infarction and then observed the effects on heart function and electrical stability over the course of 30 days.
Our findings were quite interesting. Eikonole significantly increased the heart's fibrillation threshold by 50%, suggesting it may help the heart resist irregular beats. Furthermore, we noted a threefold decrease in spontaneous extrasystole, which refers to irregular heartbeats, and a reduction of 2.5 times in ectopic activation caused by stimulation of the vagus nerve.
Additionally, we observed that eikonole improved the heart’s functioning during periods of relative physiological rest, although it did not significantly impact blood pressure or the speed of myocardial contraction and relaxation. Overall, our research indicates that cod liver oil could offer protective benefits for heart health after a heart attack, though further studies are needed to understand the full scope of its effects.
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We explored the effects of cod liver oil on coronary heart disease (CHD) by evaluating how its fatty acids, particularly the balance of n-6 and n-3 polyunsaturated fatty acids, influence heart health. In our analysis, we found that individuals who consumed cod liver oil exhibited a significant reduction in arachidonic acid levels in their heart cells, which is generally linked to better heart health.
Our research indicated that dietary fish oil could minimize the levels of arachidonic acid, a fatty acid connected to increased risk of cardiovascular issues, while promoting the presence of docosahexaenoic acid (DHA), which is beneficial for heart muscle. The results highlighted that a lower ratio of arachidonic acid to DHA in heart tissues was associated with reduced incidence of sudden cardiac events and ventricular fibrillation in experiments with rats.
Therefore, incorporating cod liver oil into our diets may potentially offer valuable benefits in protecting against heart disease. Interestingly, the relationship between these fatty acids and heart health suggests that fostering a balance between n-6 and n-3 fatty acids is crucial for enhancing our resilience to stress and promoting heart health as we age.
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We aimed to understand how docosahexaenoic acid (DHA), a form of omega-3 polyunsaturated fatty acid (PUFA), could benefit patients suffering from heart failure. Our investigation drew on a network meta-analysis that included data from 14 randomized controlled trials, comprising 9,075 participants. This analysis focused particularly on the effects of DHA and other omega-3s on heart health metrics.
The findings revealed that high doses of omega-3 PUFA supplementation, specifically between 2000 to 4000 mg daily for at least one year, significantly improved heart function. We observed notable enhancements in the left ventricular ejection fraction and peak oxygen consumption, crucial indicators of heart performance, when compared to control groups.
Interestingly, lower doses and shorter periods of supplementation did not yield the same positive results. Importantly, we found no significant increase in dropout rates or overall mortality among those taking omega-3 PUFAs compared to those who were not. This suggests that high-dose DHA supplementation can enhance cardiac function without raising safety concerns.
Overall, our research indicates that long-term, high-dose DHA can be a beneficial strategy in managing heart failure. However, we recognize that further well-designed trials with stringent criteria are needed to validate these findings fully.
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User Reviews
For thyroid health, vitamin A deficiency is linked to heart disease. Research shows that vitamin A can lower TSH levels and raise T3, the key thyroid hormone. Cod liver oil is a fantastic source of active vitamin A and omega-3 fatty acids EPA for heart health and DHA for brain function.
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Carlson cod liver oil is excellent for heart health and skin. It is easy to use and has a pleasant flavour. After regular use, my energy levels and overall well-being improved. I recommend it for anyone seeking a natural dietary supplement.
One of my preferred Omega oils. I've taken it multiple times, and I continue to enjoy the quality of this liquid form. The taste is natural and does not cause gastrointestinal issues, making it beneficial for heart disease and skin.
This high-quality cod liver oil is superb. It lowers bad cholesterol and reduces inflammation, enhancing heart health and cognitive function. It's my top supplement, especially when paired with vitamin D each morning.
Blood circulation improvement
This brand has worked wonders for my teenage children, stopping hair loss. Omega-3 fatty acids positively impact blood circulation and brain function, crucial for preventing heart disease and improving overall health.